The histology shows micro calcium deposits with surrounding fibrosis. Testicular microlithiasis predicts concurrent testicular germ cell tumors and intratubular germ cell neoplasia of unclassified type in adults 19 august 2010 cancer, vol. Concurrent tumor and testicular microlithiasis were detected in seven patients, a relative risk of tumor in testicular microlithiasis was 21. Analysis of prevalence and associated testicular cancer in taiwanese men. The most common criterion for diagnosis is that of five microcalcifications in one testicle, although definitions have varied in the past. Ultrasonography us of the scrotum demonstrated bilateral microlithiasis, a right scrotal hydrocele, and bilateral testicular masses, figs 1,, 2. Presentation this 26 yo male presented for a scrotal ultrasound as an outpatient with no specific medical history on the referral. A month ago i suffered from bilateral inguinal hernia and lead to testicular left and right imbalance, the right testis is relatively low. There is a significant association of tm and testicular tumors. Bilateral testicular microlithiasis predicts the presence of the precursor of testicular germ cell tumors in subfertile men. One case was diagnosed as having torsion of the right testis and the other case as orchiepididymitis.
Bilateral testicular microlithiasis predicts the presence. Since then, other authors have tried to link pathological findings of testicular calcification in testicular tumors and infertility to the us diagnosis of tm. On questioning he stated that one side of his abdomen was harder and more prominent, and that he had had a ct and biopsy of an abdominal mass and that the doctors thought there would be a testicular mass on ultrasound. Early ultrasound studies describing the association of testicular microlithiasis with testicular cancer. Testicular microlithiasis itself is a benign condition but its association with testicular malignancies makes it interesting.
Epidemiology of and risk factors for testicular germ cell tumors view in chinese gct or gcnis was significantly increased in the 47 men with testicular microlithiasis compared with those in whom testicular microlithiasis was absent risk ratio 8. Bilateral testicular germ cell tumors pubmed central pmc. The incidence of testicular cancer in adults presenting tm has been estimated as 10% in a prospective cohort study 1. Microlitiasis testicular, marcadores tumorales, carcinoma. It is often detected incidentally when scrotal ultrasonogram is done for various indications. Testicular microlithiasis is an unusual condition diagnosed on testicular ultrasound. Testicular microlithiasis radiology reference article. An extensive literature documents the as sociation of tm with tc, providing much discussion of the topic 710, 15, 17, 21, 27 29. Testicular microlithiasis is a rare, usually asymptomatic, nonprogressive disease of the testes associated with various genetic anomalies, infertility and testicular tumors. In our study, we found an association between tm and nst with pure dominance of mature teratoma. Malignant tumors were seen only in adolescent boys. According to our literature search, there is no specific data about doppler findings in this disease. Effects of testicular microlithiasis on doppler parameters. The first sonographic description of tm is attributed to doherty et al.
Testicular microlithiasis tm is an entity of unknown etiology that results in formation of intratubular calcifications. In the majority of cases testicular microlithiasis is bilateral. In five of the testicles, the presentation fits the pattern of classic testicular microlithiasis ctm 5 echogenic. Therefore, the prevalence of cis in subfertile men with bilateral testicular microlithiasis is significantly higher than in patients without testicular microlithiasis 1 of 210, 0. We present herein a case testispreserving surgery to treat a benign tt in a boy attained by diffuse bilateral db tm. Tumor testicular bilateral metacronico asociado a microlitiasis. Testicular microlithiasis was present in 33 patients, giving a prevalence of 0. On us of his testes, testicular microlithiasis was the only finding. Testicular microlithiasis is a relatively common condition that represents the deposition of multiple tiny calcifications throughout both testes.
It is an uncommon finding and often noted incidentally on ultrasound examination of the scrotum. Testicular microlithiasis are often multiple, uniform, small, echogenic polytopic intratubular calcifications without acoustic. Even when this rare cancer spreads to nearby lymph nodes, you have a 99% chance of surviving, and treatment is so effective that you have a 1 in 5,000 chance of dying from this disease. Testicular microlithiasis and testicular carcinoma. Testicular microlithiasis tml tml is a condition in which calcium deposits form in the lumina of seminiferous tubules or arise from the tubular basement membrane components 14. Testicular microlithiasis in rsna publications online.
The ultrasound findings in the remainder are revealed in fig. Table 2 summarises the distribution and extent of the tm. Highly treatable, testicular cancer is one of the most curable types of cancer. Sep 26, 2019 testicular microlithiasis testikyoolur mykrohlihthieuhsis is an uncommon condition diagnosed during a testicular ultrasound in which small clusters of calcium form in the testicles. Testicular microlithiasis is not associated with risk of testicular cancer in asymptomatic. Testicular microlithiasis testikyoolur mykrohlihthieuhsis is an uncommon condition diagnosed during a testicular ultrasound in which small clusters of calcium form in the testicles. Relevance of testicular microlithiasis to the testicular carcinoma in situ in the contralateral testicle japanese. The incidence of bilateral testicular tumor ranges between 1, and 5 percent.
The presence of testicular microlithiasis alone in the absence of other risk factors is not an indication for regular scrotal ultrasound, further ultrasound screening or biopsy. A number of studies show a relationship between testicular microlithiasis and testicular cancer. Testicular microlithiasis is characterized by microcalcifications within the lumina of seminiferous tubules. Data analysis showed that testicular tumor prevalence was 22. Bilateral testicular microlithiasis predicts the presence of. Case reports have been published that demonstrate diagnosis of tm and a concurrent testicular malignancy 6,7 as well as a patient with diagnosed tm who subsequently later developed a testicular tumor. Significado clinico e implicaciones terapeuticas testicular microlithiasis is a rare condition usually diagnosed by scrotal ultrasound and associated. Ultrasound is recommended in the followup of patients at risk, where risk factors other than microlithiasis are present. Two weeks ago, after bilateral hernia surgery, the right. Tm has a prevalence of 2% in boys who undergo scrotal us. Microlitiasis testicular multiple bilateral asociado. During followup no testicular cancer developed incidence 0 %, 95 % ci 07 %.
Given the site of the biopsy, a testicular primary is most likely, if clinical examination is negative, other primary germ cell tumour sites should be investigated. Bilateral testicular microlithiasis is indicative of cis carcinoma in situ in subfertile men. Images of the right testis demonstrated enlargement, diffuse microlithiasis, and a homogeneous, hypervascular mass that replaced the majority of the testicular parenchyma, fig 1. Create marketing content that resonates with prezi video. Subfertility is reported to be a risk factor for a testicular tumor. Doppler findings of three cases of testicular microlithiasis during last two years in our institution are presented. It is most commonly bilateral, classic type, and stable at followup studies. Bilateral testicular microlithiasis doctor answers on. Mar 08, 20 the incidence of bilateral testicular tumor ranges between 1, and 5 percent.
63 1101 577 1355 143 710 1571 917 771 237 494 429 1220 832 49 904 186 790 1287 560 199 179 1554 256 782 1415 1463 1174 1024 396 1374 1109 1489 567 1081 82 80 242